Chris\'s notes – a lot of good info

Forgot to say, some advice on how too increase t4-t3 conversion which

you want since t3 is the much more active and stonger thyroid hormone

of the 2.

*Increase exercise only if energy is present that day. Being stagnant will

make it worse.

* Add in Apple cider vinegar or betaine acid before meals.Low stomach acid

go hand in hand with hypothyroid due to less body warmth.

*Tyrosine,Kelp,Selenium methionine all help convert t4-t3.

*Increase citrate acid from source grapefruit,lemon,orange juice which act

similar too stomach acid which help t4-t3 conversion.

The acv/betaine+ citrate fruit source will help assimilate food+supps

better to get more from it as well! D

yeah 12000iu d3 since i was right at bottom.. oh forgot to say must be

liquid emulsion version not caps/gels since wont get absorbed for ppl

with thyroid/gut/liver issues! Lef.org made one just for us hypothyroids D

*Something just popped into my head… your tylenol isnt working

from lack of stomach acid due too low thyroid. Possibly with liver issues

its even more effected. If your chick still comming up shortly then i would

eat some oranges,grapefruit etc or if have acv take 1tbsp before

tynelol, should help assimilate for more bioavalabilty.*

hmm hard to say .. wish could see histamine blood test but i cantry figure out

homocysteine pattern from your MVA test if histamine is high or not.

Generally undermethylators have higher histamine levels but not always, tricky:)

About the -shbg >+free estrogen it is possible depending on ones biochemistry

and if e2 isnt reduced along with it and how much DHT is being converted

from increase of free Test, will go on more about dht later.

Also lowering shbg can lower e2 with some

folk, others, it can cause a rise in total estrogens not just e2 but e1(estrone)

& e3(estriol) sincelike you say less shbg binding too it>more free total estrogens.

——————————————————————————————–

I dont know Nirvanas e2 level so cant really recommend an ai but since

yours is high at 48 defo need some form of AI.

——————————————————————————————–

More paste :

ahhh …I forgot to say previously Activate has a natural aromatase inhibitor in it

which lowers estradiol called Brassaiopsis Glumerulata. Many studies done

on this. I suspect small dose since they only give a total amount on a mixture

of ingriedients but add this with sustain alpha and that should lower e2

but not too low which Dim can cause.

Also remember about the higer free Dht>lowers e2 receptor sensitivty, thats in your

favour as long as your body has enough 5-alpha reductase enzyme too convert

the extra free test into the free DHt metabolites.The rheins urine test would

come in handy here and show you how much is being test is being converted too DHT!

As long as 5-alpha reductase is working the increased dht/free dht metabolites

from lowering shbg will desensitise e2 receptors opposite reaction of high progesterone

in males which it increases e2 receptors n thats why high prog+high e2 symptoms

are usually exact same.

———————————————————————————————-

Frenchi I dont know your Test-Dht ratio but with your low free test,high shbg, high e2

then DHT should be well below mid range.

Some q’s for ya just too see if any reduced conversion of test>dht conversion.

Do you have any experiences with hair loss drugs like Finasteride, Propecia?

Frenchi any past experiences with preg/prog?

Any past experiences with steroids?

Any difference in hard flacid physical changes when you have abstained

for a period of time say 4-7days compared too just after/aday after ejaculation?

*4-7days or they day you feel the urge is too much*

Yep thats why i brought up methylation pathways and liver being backed up and

Han is right, if cofactors of methylation arent present or when methionine pathways

are blocked then gluthathione may be depleted and bodies main detoxifaction

comes to a halt.

(This is just simple breakdown)

Add in an AI like dim which draws e2 from bloodstream into liver lowers e2 in bloodstream

for timebeing but the liver is unable too excrete/urinate it out due too undermethylation

and then e2 would eventually increase.

Keep the Nac going too boost stage 2 gluthathione levels, thats biggie and Sam-e too boost

methionine stage 1 gluthathione pathway plus it helps that sam-e =is the most potent methy

supp doner available in increasing gluthathione, bodys most powerful detoxifier.

If your also taking tyrosine/tryptophan sam-e will increase conversion

into dopamine/serotonin>melatonin.Increase of dopamine>lower prolactin>higher test,

increase conversion of serotonin+melatonin, deeper rem sleep, more hgh being released

more recovery and more morning cortisol which you are deficient on.

Its interesting that you, Janek, Nirvana and myself in past had low morning cortisol

and share similar symptoms… i wonder if you experience a sudden short* rush of energy straight after

ejaculation like i did and recently found out that Nirvana does as well?

If Nirv ejaculates at night he says cant get too sleep and then morning/day after

he feels drained,dead etc

Also brain fog was common for him after orgasm which prolactin can cause

and you have high prolactin too.

Heres my paste that was sent too him, sure he wont mind sinceyou both

already are pming

—————————————————————————————————–

This is test+dopamine dropping from abnormal increase in prolactin plus you already

have prolactin and i bet like how i was before for yrs your prolactin increases

several fold even more after ejaculation ie the sudden brain fog

making refractory time way longer than healthy males!! Feeling wired is the

high prolactin symptom as well along with low dopa+low test.

Adrenals may be taking a hit depending on your baseline level & if depleted in synch

then it would take a big toll on ya majority of time instead of refreshing you which it

does in healthy males.

Plus feeling wired unable too sleep can mean adrenal cortisol surge increase after

ejaculation hence you being unable to get to sleep at night after. What happens is

with adrenal fatigue folks cortisol levels alreayd low and when one goes through

ejaculation process it uses a certain amount of cortisol. Adrenals try too make

up for it right after hence the not being able too sleep issue but instead

ACTH is malfunctioned and causes too much of a *short* spike uses it

up quickly right after for small period and then after or next morning/day

the feelings of drained,fatigued kicks in due too low cortisol.

I had saliva cortisol test done 1hr after ejaculation and it was above the charts!! LOL

was surprised too say the least…

Next morning took it and it was below the charts :/… this experiment seems to make

sense with my theory and i suspect yours too from your symptoms.

—————————————————————————————————

If your other methylation cofactors like b12,b6,folate, are healthy then enables sam-e

to do a better job too unclog your liver but worse situation and they are all depleted then sam-e might

only boost gluthathione alittle as itneeds some helps from his meth buddies.

Since you been taking both nac+sam-e for a while now i think dim should work but lets say it

doesnt or lets say you want to try a different route.

Arimidex from here :

http://www.alldaychemist.com/search.php?search_query=Anastrozole

Nolvadex may work but is more than half as weak too adex:

http://www.alldaychemist.com/search.php?search_query=Tamoxifen

For emergency backup incase of sudden lover arrival, good price cialis :

http://www.alldaychemist.com/search.php?search_query=tadacip

Says it nots for consumption in Usa so all you do is after you purchase

send ADC an email too confirm its not for consumption and they will

send you it D

Problem with these AI meds it can drop e2 like a rock … shame ADC dont have

the 0.1 adex pill as easier too manage since im not sure how accurate dosing

is if cut up the 1mg adex pill, not sure if evenly distributed at least it wasnt

with my yrs of taking adex.

If you want too try adex then no more than .25mg quarter a pill and

see how you feel for next few days.

If e2 drops too low for ppl with hard flacid it will effect it big time

and takes ages too get some normality back, up to 2 weeks or more.

hmm .. mva test would show which direction best too take, depends on your

liver tbh.

hehe sounds like the tyrosine dopamine spike is kicking in!! xDD

Hey m8, i think you did right thing and plus this is still early days after just finding

out some personal dna info so imagine what you will be like when you get following

improved in couple months or less :

High Shbg

high e2

Adrenal imbalance

Hypothyroidism

Low free test

Most likey low DHT

Think about how many of these effect hard flaccid … actually they all do!!

Got to give ya credit on still keeping these areas still open!! xDD

hmm possibly both tylenol+curc lowers pge2/cox 2 levels too low and lowers your

test+dht since body needs some too make testosterone from saturated fats and arachidonic

acid. It may work better if sufficient free test+Dht is present than if low, actually im sure

it would but just my theory…

i think its all about finding the right balance of everything high sexual hormones and

low inflammation status from improving liver methylation pathways so your SHBG and estrogens

dont end up being clogged up in there. Plus fixing adrenals and thyroid will.

How did your temp testing go?

AWESOME!! xDD yep boosting dopamine and gaba will do that and majority of folks

with se/pe are low here so nws on adding a little esp when it helps ya so much!

LOL just like weed …!! oh man that is some good shat .. D

————————————————————————–

Me:

“Ok so I cleared my mind a bit.. made a list of everything you mentioned.

Basically the key supplements are:

– The Activate Xtreme – to boost free T and lower SHBG

– DIM – if neccesary, to keep E2 down

– everything for adrenals – relora, B5, Vit C, and so on..

– once get mva test, we’ll add vitamins for thyroid and more aminos. ”

Chris:

– AX defo need due to your high shbg,low test,high e2,high prolactin.

Forgot too mention AX already has natural AI in it called brassaiopsis glumerulata but

have no idea of the amount they are using.Dont think it will drop e2 too much so need

something else …

oh ya … also forgot too mention AX has both L-dopa 95% extract and 20% extract murica pruriens

which are the strongest natural supps too increase dopamine and then reduce your prolactin

and hopefully increase total test numbers.

Lastly it has maca root 20:1 extract in it too which is commonly taking by peeps with adrenal

fatigue and some swear by it that makes a big difference for energy levels, libido recovery etc

Also some notice much bigger ejaculation loads from Maca root and maca is commonly used in the increased sperm supps! ;D

Onto your high e2… you have a few choices all has its strength and drawbacks:

Take dim too try lower e2 now and hope cofactors are present. Depending on when MVA test is done

and if dim is taking too long and your liver is backed up from lack of b6,b12,folic then

could increase e2 but this wont happen overnight takes couple weeks at least.Plus with already taking in

Nac and Sam-e your already increasing liver detoxification in a big way so i doubt e2 will increase

from Dim and im sure the folks who did have an increase werent looking at their liver pathways.

Try adex/tamoxifen at small doses possible and hope e2 doesnt drop too much.

Good thing here it will def lower e2 since much stronger than dim and you can notice e2 dropping on the same

day but usually takes a few days where as dim may take a few days too drop or even couple weeks depending on how fast your metabolism

is and also on the liver.

Side effects long term from either should be very low if any at all considering small dose

of adex needed but if were up to me i rather stick with all natural as possible.

I think best route is too see when MVA test is done and wait for results or if you know results are comming

back within 2 weeks then no worries dim wont be a problem in, increasing estrogens in this small

timeframe.

Adrenals fix looks good plus the Phosphatidylserine taking in evening and then 2-3hrs before sleep.

Im almost positive you dont need any cortisol med and this will sort itself

out in time and right supps,lifestyle and sleepin pattern,improved sleep etc

Yeah mva test onto methylation fixing your liver which will also help lower e2,shbg, lower toxins,

get the liver flushing out fats quicker and then hopefully your thyroid building blocks

are low so no thyroid meds are needed.

Let me know what direction you gonna take with the lowering e2

Chris

*NOTE FROM ME: DON’T START APPLYING WHAT HE SAYS UNTIL YOU’VE READ ALL THE POSTS UNTIL THE END BECAUSE HIS MIND CHANGES LATER ON BASED ON MORE OF MY RESULTS AND BASED ON SOME THINGS HE REALIZES HIMSELF LATER

I use this mag rub :

http://www.calmnatural.co.uk/magnesium-rub

It has 450mg per ml which is pretty good dose and i do 3ml before i sleep

and also 1tsp(450mg) of now mag citrate during day.

————————————————————————————–

Im expecting too see some blocked liver methylation pathways from your mva test also some conversion issues and lack of hormone building blocks. If this is case then optimising these should help restart proper methionine>gluthathione production

for efficient liver detoxification to prevent and quickly get rid of excess fats, liver bile> proper cholestrol conversion too all hormones ie adrenals pregnenolone,prog,cortisol,dhea

sex test,dht etc toxins, bad bacteria> metabolism n immune system,excess hormones like e2 shbg etc

reduce inflammation from clearing all toxic buildups in liver.

This should help filter out the high SHBG+E2 levels and should also keep higher total testosterone, free

and dht for long run. The AX+sustain etc is for little sex hormones kick to get it started faster and hopefully

wont need for long term and you can wean of them slowly or stay on a lower dose Eod long term.

However if your mva tests come back healthy then isnt problem with

liver, gut etc but rather more serious hpta/pituitary disorder and long term use may be required for

optimal health but i will be very surprised if all liver methlyation cofactors for

glutathione production come in all healthy simce people without Se/pe/sexual health probs

already have impaired glutathione detoxification pathways and actually at least 40-50% of population are

undermethylators and only 10-15% are overmethylators! D:

With sustain you can do 2-3pumps(1-2pump on testicles) 5days on 2days off so lasts bit longer, bout

2.5months or so. Also PP drops sustain pricing too 30bucks 3-4x a year usually

around New yr, Easter,Thanksgiving summer holidays etc so could try catch it right next time.

Looking at your hormone test results again … i suspect possibilty of thyroid med being needed

unless thyroid building blocks are all extremely low like iron, copper, tyrosine, selelium,iodine etc Your tsh is so high and free t3 very low so this is very important for you too see

as soon as the results come in… sounds wierd but im hoping all the above are all right at the bottom so you dont have to go on thyroid med for life!!

I wonder if you have noticed much reduced warmth around the genitals area? Do you also experience during hard flacid days the penile, testicles area are colder?

i also stopped sweating during self practise and much less sweating during physical

exercises until thyroid was optimized…

I experienced this alot during my hypothyroid days same as the cold hands n feet but at same time my body warmth wasnt too bad unless was morning and i hated the cold mornings since my morning body temp was very low…

Frenchi you manage to find that thermometer ? ;D

High psa is also concern for prostate cancer but this will drop once high e2 drops since prostate

is highly sensitive too estradiol.

*I ASKED HIM WHAT SUPPLEMENTS + MEDS CHRIS IS ON NOW. VERY INTERESTING:*

2.

Sure not a problem Frenchi!

Trt restart since Dec:

Hmg 75iu x3 a week for 1 month(short n powerful kick for mainly fsh boost for

sperm production, bigger testicles and some lh boost for testosterone production

via leydig cells and also hmg can help sensitise the leydig cells)

clomid 12.5 x3 a week for 2months at last week of hmg too increase fsh+lh

via natural signaling from the pituitary gland unlike hmg

sustain 2-3pumps aday 5days on 2 day off (long term since need to control

e2 and keep fsh+lh signals up so natural production hopefully wont drop

once off clomid)

Toco-8 1xscoop ed too improve leydig cell sensitivty.

With previous several natural test restarts i failed too keep the increased

test levels and i think it was due to not keeping e2 from rebounding after

clomid and also didnt keep lh+fsh up so hope this time it works .. but so far

its going great, fingers crossed!! ;D

Rbc fatty acid test showed high epa+dha levels from fish oils 3g for over half a decade,

very low arachidonic acid levels (too clean dietas well)due too fish oil competing with it, as well

as very low gla levels and saturated fats.

Increased ala+saturated fats with diet beef sirloin/tbone/topside steak ed, 6-10whole cooked one side eggs ed,

organic butter 1tbsp ed or more since use it too cook the eggs, beef etc, 1tsp olive oil x2aday+

EPO 1g x3 ed for more pg2 too pg1 conversion due to sudden increase of AA+sat fats

which can convert too pg2.

All increase ala +saturated fats for building blocks too convert too more testosterone naturally and i think

this is another main reason natural restart is going much better this time with no rollercoaster depression like symptoms from previous restarts.

I have low cholestrol from overtraining, bad diets and possibly overmasturbating from age 11

so i need too maintain high chol diet just too get chol into healthy range

so it can be converted into hormones like preg,prog,cort pathways and test,dht pathways etc

So main thing for me is keep chol up which is quite ironic considering how much the media

portays chol as the bad guy ;D

I had tanked fully depleted cortisol readings but now n again i had 1 decent reading out of the 4 just

barely in range .. so ive experienced many adrenal meds like cortef, hydro cream, medrol, preg pills, cream etc.

Cortef was ok but had too dose up quite regurlary and sometimes would cause a spike and crash or wouldnt sustain long enough. Medrol didnt seem too increase cortisol and

hydrocort cream worked but needed alot.

Preg cream seems to be best for steady, consistent cortisol boost as well as preg, prog etc

which were all depeleted from rheins 24hr urine test. As long as dht is sufficient and preg isnt backed

up into prog instead of cort and then will cause worsening of ed/hard flacid, high e2 symptoms etc

15mg morning, 5mg after shower ed for adrenal pathways. Lucky i dont need

more since some guys need up to 100mg or more a day.I think optimizing thyroid can help

absorbtion so maybe other folks dont absorb as much hence needing higher dosing … maybe

possibility .. or are fast hormone metabolisers….

I need dhea cream dispite preg cream as preg doesnt seem to convert into dhea for

me but usually does for others so i do small dose 10mg ed since helps libido alot as well as having more vascular appearance,

muscles being pumped 24/7, bigger, veiny, larger flacid and actually seem to help produce an erection much quicker when it comes down to the business!D

Possibly increasin dhea may increase eve more libido, anabolic effect long as liver can handle it and not be converted into estrogens since 10mg is very small dhea dose. Dr Crisler has some of patients on

100mg a day! D

My thyroid levels were high tsh and low free t3+t4 similar too yours but tsh wasnt as high, freet3+t4

around the same. So once was on cortef for 4-5 weeks added in armour slowly.. Once armour started to be

short in production changed too nature thyroid and i was at 3grains aday plus 50mcg t3. Had issues with

absorbing NT due too the celulose binders in it. Now have dropped too 2gr only with product called

candex too help absorb thyroid med better and by adding in extra copper, iron on top of some selenium,

iodine, tyrosine ed it may have helped reduce the thyroid dose, Fantastic!! ;p

Free t3 last was slightly above top range and i like too keep it here for optimal energy expenditure,

body warmth, optimal metabolism, lower bodyfat, sexual function etc

Most likely thyroid is for life since i much prefer higher t3 than mid/low range for optimal health! ;D

I suspect always had or was prone too slight adrenal+thyroid malfunction due too always having alittle

too much excess bodyfat around stomach, lovehandles etc dispite years of strict hardtraining in boxing, weights, clean diet etc

Liver methylation supplements for healthy liver. methionine> gluthationine for optimal detoxification production>

reduced inflammation,improved metabolism etc:

Just about every cofactor for stage 1+ stage 2 glutathione production were all very low.Methylation pathway

can be seen here :

http://www.holistic-back-relief.com/mercury-toxicity.html

stage 1 b9/folic,b6,b12,methionine

stage 2 cysteine,sulfur,taurine,zinc,glycine

This confirmed extremely low liver detoxification processing so i needed to increase this

by adding in all the supplements above except folate instead of folic,p5p instead of b6 since liver wasnt able too convert to bioavailble form.

Sam-e was taking for 400mg x2 a day for around 2months then subsituted for methionine 1000mgx2 aday

tmg 650mg x2.

folate 800mcg ed

p5p 50mg x2 ed

b12 jarrows methyl 2.5mg x2 ed

Nac 600mg x2 ed to help low sulfur as well

taurine 800mg x2 ed also converts too gaba

No glutamine due too high ammonia, had and still have slight issue with high glutamine too glutamate conversion.

Zinc picolate 25mg x2 a day too help clear excess estrogens once liver methylation was increased.

Some folks dont experience excess e2 clearance and i suspect blocked liver methylation similar

too dim increase estrogens in some.Once increase magnesium levels for couple months added

in calcium-d-glutarate 500mg ed which helps lower e2 or keep it in check

Also it has seem to help alot with alergies too dust, dog n cat hair, sinuses,stuffy nose,itching,flushing,

red rashes etc i suspect it has lowered my high histamine which is responsible for inflammation+pe. Possibly

why that i have been able too lower tynelol too twice 500mg a week and tbh dont think i need it anymore

for PE but slowly weaning off too make sure

Core seems much tigther, more frequent bowel movements,very happy with my digestion, metabolism etc

Less sensitive too paint, perfume, aftershave and overall much less alergy reactions etc

So possibly have found root cause of the problems mainly inflammation causing PE dispite having had my hormones optimized! Awesome!! xDD

Too make sure digestion can keep up with higher protein diet too increase muscle mass:

Super digestive enzyme+oxbile 150mg too aid in cholestrol production and remove

excess bile from liver: 1 tab b4 each meal

1-2/ 1tbsp acv betaine tabs each meal

I had slight insulin resistance before where too much insulin was roaming in my bloodstream and not making

into the cells so my proten synethsis sucked and made my hgh action more catabolic than anabolic.Good thing dont need no supps for insulin/glucose management anymore since due too lifestyle n diet changes.

Amino acids

inositol 650mg x2 for liver detoxifer as well as proper production of serotonin levels.

Tyrosine 2gx2 for dopamine, reduced prolactin. Only works if body has enough methionine/sam-e

otherwise wont convert into l-dopa into dopamine.

No more tryptophan/5htp or gaba no need!!:

No more adex after chasing my e2 levels for yrs … thank fwock!!

Now no more shrinkun nuts and smaller loads from being on TRT!! D

With improved liver methylation detoxification process less inflammation and has helped

PE since being able too take less n less tynelol… so is Pe due too inflammation more

than hormones … hmmmm

Frenchi I think optimising your hormones will fix your hard flacid, produce much stronger n frequent

erections and the inflammation should help sexual stamina as well as all other general health improvements.

oh .. forgot too recommend in getting a head honcho or fleshlight if can afford the more expensive

toys for practise and confidence booster before attempting real thing again. Much more realistic

feeling than simple masturbating and the feeling can not be compared, once i bought it, i never masturbated again since it was so boring compared to it plus gives you a guage on your progress.

Heres it for decent price :

http://www.amazon.com/Sue-Johanson-SE-9573-00-3-Johansons-Honcho/dp/B0010EI2HI

If you use the head honcho make sure to get some thick elastic bands about 5/6 wrap all the way from top too bottom, more at the front too make it more realistic tighter fit.

ahh yeah defo!.. 250mg mag wont do much but 2g oil spray will make big

changes for your sleep, recovery,adrenals etc I get mines from Uk source which is more

of a liquid rub but has 450mg per ml and i do 1.5gish before sleep and only cost about 30bucks,lasts about 3 months so not bad cost wise. ;D

Thats why your cysteine levels arent too bad but i had thought b4 testing results you would have

the less severe stage 2 gluthathione undermethylation but from results it confirms you have

the more severe stage 1 gluthathione undermethylation … but good news once you fix this

liver pathway with folate and b12 you will absorb everything much better ie liver taking in more of the

good and flushing out more of the bad.Frenchi i remember you mentioned tylenol not working as well

as before which low folate and b12 causes.Also other types of meds/drugs wont work as well

due to this liver pathways being blocked and not working correctly. Once you fix your b12 and folate

everything else you take will work much better and that includes supplements hence why

you dont experience much from taking supps just like myself b4 and just about everyone else with stage 1 undermethylation.

No motivation will be from adrenals,thyroid and the low free testosterone from high

shbg and e2. I think your body can handle working out when its not loaded with extra stress with studying, semester etc With some stress involved training goes out the window like you need extra cortisol,alot more thyroid and alot more free testosterone.

So these symptoms matches your cortisol test

where your adrenals wasnt totally fried but just stressed out and needs a wee break and thats where cortisol comes in!

wow .. Frenchi your genetics cant be that bad if you stopped working out for month and still have the muscle

and not put on any fat plus the hypothyroid and high shbg+e2!! xDD

2 Tylenols helps by lowering inflammation which your liver isnt sorting out naturally due to low b12 and folate.

Causes a methyl trap in high homocysteine just after stage 1 glutathione pathway and just before stage 2

and this causes inflammation which the tylenol helps with but not as much as before, possibly tylenols

side effect was lowering your livers gluthathione production via b12 and folic acid even more to point you dont receive

full effects. Some folk who take viagra for yrs end up with diminishing effects but once add

in some folic/folate acid it starts working properly again.

I had previously thought it was your gut and low stomach acids being issue for the less effects of tylenol but we know now from results its the undermethylation at fault.

Once you add in some b12 and folate it should help this alot and also help bring back full effects

of tylenol, if tylenol is still needed.It may be best to stop all tylenol,booze etc for that 1st month to let liver

absorb as much of the b12 and folate as possible. Since they can be easily oxidised if your adding

in anything into ur body that lowers gluthathione production like tynelol,booze,coffee etc so would just be wasting the supps in a way.

ahh for the tryptophan … you can take either tryptophan or inistol but after least 1 month

of b12 2.5-5mg sublingual,folate 800-1600mcg.The liver is most important as you dont want

to back itup even more by adding too many supps so want to clear it out first.

Fact that you dont have any allergies, symptoms,extremely low b12,folic and nacin confirms

low histamine, wouldnt even need blood test to confirm as all signs are there!

Along with b12 and folic add in some niacin but dont start them alltogether so you

know how you respond.Take niacin after you got use to the b12 and folic.

Just a wee caution, your face may end up feeling all tingly similar to taking high dose gaba ;p

You need some histamine to have proper HPTA functioning especially for the sex androgens

so this is another root issue.Low histamine can lead too causing

E.D ,lowered libido,less intense orgasms etc Also you need some histamine to make neurotransmitters

serotonin and acetylcholine.Serotonin helps with pe,feeling relaxed and acetylcholine helps with libido & actual erection

strength and helps alot with hard flaccid as well. I eat alot of lightly cooked eggs everyday and sometimes

a few raw organics before sleep or if not i subsitute it with some 1-2g choline tabs sometimes.

Now that im thinking more about it maybe you wont need tryptophan or choline if you can get

your b12,folic and niacin high enough since ur liver will make the rest from it… will have to see how you get on ;D

hmmh .. its a tough decision but after my experiences and what i know now i personally

would recommend natural route first but if you can get thyroid for free then might actually be better to

try both supps and 2grains of armour for quicker improvement in health and optimized thyroid production.

You could still try wean of armour in 1-2yrs depending if the supps are effective enough later on

Looking at your results again :

PSA: 1.9 range: <0.5-4 (optimal 0.5-2)

Free T4: 1.8 range: 0.7-2.5

Free T3: 3.1 range: 2.5-6.5

TSH: 5.5 range: 0.5-3.0 * <— think the range was supposed to be 0.5-5

TPO: 16 range: 0-150 (70-150 borderline)

Your tsh is already trying extremely hard to make thyroid cells but there were no building blocks

in your system apart from iodine so thats the best your body could do. Now imagine

what it would do with selenium,copper,iron & molybendum.It may not reach the absolute

top range but i reckon would hit just above mid range within 2-3months.

So possibly that extra bit of thyroid i suggested would hit your optimum peak and after a yr or 2 you

wont need it but just the thyroid supps but at a less amount because ur liver methylation stage 1 pathway will be much be better by then.Heres hoping!!

Also the copper,iron,molybendum and selenium help alot of other things apart from thyroid.

Heres a few links already in my bookmarks:

iron and copper work together:

http://lpi.oregonstate.edu/infocenter/minerals/copper/

http://calosol.com/copper.php

http://www.whfoods.com/genpage.php?tname=nutrient&dbid=53

folic defiency :

http://www.innvista.com/health/ailments/anemias/folicdef.htm

Peoples experiences on Molybendum:

http://www.healthyawareness.com/articles/about-vitamins-minerals/about-molybdenum.aspx

Complete diagram of methylation cycle and diff types of methylation :

http://www.heartfixer.com/AMRI-Outcomes-Non-CV-Autism-Methyl%20Cycle.htm#CBS:%C3%82%C2%A0%20Cystathione%20Beta%20Synthase

Methylation can be hard to digest at first but keep reading at it m8 as the methionine b12 and folic sections will be extremely helpful for you!

Frenchi i forgot to say alot of your mva test results relfect some form of heavy metal poisoning

especially the low b12,folic,copper,iron,selenium etc points to mercury.

You havent had a history of high fish consumption especially tuna,tooth fillings etc have you?

Prob nothing but thought i’d make sure

Only other down side i can think of is absorbtion when one has candida or leaky gut symptoms.

Then one will need to take high dose celulase supplement to absorb it properly even if taking sublingual

due to the binders in the thyroid meds.

hmm.. just thought of something! If you can get thyroid meds insured from doc try also

get cortef and nvm the preg since preg can make hard flaccid worse!Cortef wont affect hard

flaccid at all and plus would save u lot money on buying preg cream,pills etc!

You could do this :

Start cortef 5mg first thing morning behind tounge and then 5mg 4hrs after.

Since we dont want to keep you taking it for life keep at doses 20mg or below

so say max 10mg am, 5mg midday 5mg 4hrs later.

This will help give your adrenals a nice long rest for 1-2yrs then you can try wean off

or whenever you feel alot better.

Do this for a month on cortef 5mg x2 a day for 4 days then increase too 20mg max

if you feel you need more. Will help inflammation so may help hard flaccid as well.

After 3-4 weeks of cortef add in thyroid med at half a grain max for 4days then increase

to 1 grain total for 4 days then again add in half a grain max. Most people can tolerate half grain dosing

but some can only handle 1/4grain jumps at a time but i think with your adrenals being not too bad you will be fine.

Work up to 2grains if need but no more since above this you have much less chance of successfully weaning off.

Also start adding in thyroid supps same time as starting thyroid med selenium first,molybendum,copper and then lastly iron.Try give few days inbetween.

Remember that cortef and thyroid med wont work as well as it should at first since you have low

gluthathione production from low b12 and folic so possibly after a month of b12s and folic

you will notice the cortef and thyroid effects more.

So if you can get cortef and thyroid armour or nature thyroid from doc insured start of with b12,folic first or same time with cortef and then 3-4 weeks after cortef start

thyroid med slowly as i described above for less chance of side effects plus thyroid supps.

You can also decide to take sustain alpha topical along with cortef so adrenals at least

have some extra cortisol to handle the extra testosterone,dht production.

Lastly would still recommend dhea cream biovea/lifeflow brand at 1pump a day as helps alot with being more physically vascular including helping helping hard flaccid being more plump etc

Great stuff, phew!!..no experience with kegels or any that funny malarky!

When you see endo Frenchi push hard for either :

Erfa thyroid

or

t3 cytomel + t4

These are the best absorbable thyroid meds the others like new formulation

armour, nature thyroid, thyroid s etc have more celulose in them meaning

less absorbtion with some peeps.

Yeah that be sweet if endo can run some tests and even better run some other

types of hormone tests! Hopefully this guy pulls through for ya, wish ya best of luck!

ahh nice idea on hcg … it would increase your total testosterone but too how much

im not sure since depends on ur liver e2 conversion.With your undermethylation backed up liver and already high

present lvls of shbg and e2 you would most likely have high aromatisation of

the lh too e2.

I reckon if you were to go this route would highly recommend start with

smaller dose for less lh>e2 conversion say 100-150iu eod or

5days a week.I think you may be ok with this smaller dose, less e2 conversion

and less chasing e2 24/7.Dim with the other liver methyl supps should keep e2

in check here without an ai, hopefully, but you may end up needing an AI since

hcg can horribly increase e2 in some folks, it really depends on how you do

on the liver methly supps to increase your undermethylation cycle

and unblock all the pathways let out the already high shbg and e2 hormones.

The other slight issue im worried about is your experience with pregnenolone

making hard flaccid worse.Janek didnt experience this with preg i dont think.

The hcg also increaes

progesterone which preg also increases.

If enough thyroid is present or

free t3 lvls are present then the progesterone will increase too cortisol.

Janeks free t3 lvl was higher than yours Frenchi and hes only 19 so the conversion enyzmes

are still in tip top shape.With not enough present free t3 lvls the hcg

may stick at increasing progesterone only and no cortisol increase, thus lowering dht lvls and then

hard flaccid symptoms increases and libido drops.

Possibly if you defo want to do the hcg route, wait till you have started

thyroid replacement so better prog> cortisol conversion takes place.You could

try hcg first before thyroid but i wouldnt recommend for the above reasons, not

worth the risk in my opinion, could make yourself worse.

With SA and AE supps you will defo experience lowering shbg and higher free

test.Altho it wont increase total test lvls as much potentially as hcg and possibly your idea of hcg

of increasing total test as well could bring you back too even better

sexual and general health just incase lowering of e2 doesnt increase total

test enough too optimal levels, this like an additional backup.

hmm good food for thought… Possibly instead of Sustain alpha

go with low dosing hcg, 100-150iu 5-7x a week since looking at your

total t lvls its bang on the mid range so an increase here would improve your well

being dramatically.

However before hcg i would highly recommend starting the dim too lower

e2 plus liver supps so its not being backed up and thus increasing e2 which happens

if liver cant shift it out.Adding hcg without the dim and liver supps

will cause chance of higher rate conversion too e2 so would recommend at least 1 month

on dim and liver supps before hcg.

Plus start the activate/testopro before hcg too ensure

enough DHt is present too counter any possible increase of progesterone from hcg

subq shots and also for lessening shbg>higher free test lvls.

If possible, endo will get you the good thyroid meds listed above then give the thyroid

replacement at least a month as well before hcg, that way you have everything covered

as much as possible incase of any of the hcg negative progesterone, estradiol side effects.

Frenchi if you want to be bulletproof safe then 1 month of dim plus liver supps and then retest e2 see if it actually lowered.If so then hcg is np.

I think this route may work better than previous long as your liver can reduce

the e2 lvls enough and keep e2 conversion at bay so it can do its job at the other

detoxification pathways too keep inflammation low as possible.

Good question m8 … n its a tricky one due to the hard flaccid symptom

and how much preg actually gets increased into prog and how much it

impacts your hard flacid plus whether or not the prog

increases into cortisol…its not a risk I would take, having tried the preg myself

before sorting the rest before, you would like most likely

make hard flaccid worse!

Frenchi what was your dht reading again??

Also are you able to test preg+prog blood? .. may have to get doc to do the preg and DHT as dont think the ZRT do these 2 tests unfortunately.

If you have high DHT you may get away with it and with ur high shbg low free

test its most likely your DHT will be below mid range so again preg not worth the risk.

hmm.. yes you make a good point bout the e2 it does have

to be lowered otherwise adding in preg increases prog which can make E2 receptors

more sensitive esp if one is hypothyroid and plus we have too see first how much dim+methylators opens up your

detoxification liver pathways to clear the excess e2. I know AI would drop E2 like a rock but rather not go the AI route for life as that just adds more inflammation in your liver

and lowers your gluthathione levels which are already very low from your MVA test.

I would give the thyroid 4-6weeks and then retest the cortisol x4 saliva and see how it has been affected, it can go up or down and your midday and afternoon is quite high and we

hope it balances it out into your morning cortisol level, that would be the perfect outcome!! D

**If you can get cortef only 5mg morning dose will be needed, if not I think with your recent improvement in the sun your thyroid med will be able to recorrect the cortisol without the cortef/preg**

Im more concerned with your dhea adrenals rather than cortisol after relooking at ur dhea lvl.Remember the ZRT top value is 200-300pts lower than optimal and maybe

for ones like us we need more .. i found i did and keep it around 500ish with dhea cream and micronised pills, helps bring up the gas for libido so to speak

so Im able to perform at me best everyday and also for feeling more

physically vascular all around and better pumps at the gym.

Best thing to do would be instead ordering preg cream order the dhea cream from biovea either the DHEA plus or DHEA Male … i think the male one has more abour 30mg each

pump last a month. Increasing my dhea to top range really helped with hard flaccid

and just having alot more fuller plump flaccid in general. Increasing Thyroid,DHT, total+free

test,mid range e2 completed it and then sorting out the inflammation with addressing

adrenals if need be, opening liver pathways and previously with some tylenol did the complete job

for the PE side and just generally having more energy, insane recovery,

having a good laugh etc

wow … no idea Janeks planning on test.. that hopefully wont be needed until hes a senior citizen!! ;D

With the small hcg doses it should take until hes least 40+ for trt but maybe something has came up that I dont know off…

Alright that’s everything.

*For anyone that doesn’t know Janek is JS. JS is a member of the board. His new name was YO in his later posts.

*Its been over a year since I talked to Chris. I was on Vit C, B100 and such and my adrenals recovered naturally it seemed, cuz when I retested them cortisol looked a lot better. So I may not need Cortef but I wanna retest adrenals again to make sure.

* Everything else I’m still planning on doing.. like thyroid meds.. DHEA cream all that

* Obviously I can’t afford ALL the supps Chris mentioned so I’m only gonna get the ones I think are really needed for me. All you should do the same. Pick the ones you think are most important to your case if you can’t afford em all.

* I decided not to go the HCG route for now. I’ll see how far I’ll get with the supps and meds. If it doesn’t work out then HCG is my next step. Since Chris is off TRT now and is doing fine.. it makes me believe that it can be done without TRT.

* I started taking Niacin NOW brand (flush free from iherb) 250 mg a day about a week ago. Feeling even better mentally. It also has some Inositol in it which probably helps too. My hard flaccid’s started looking better too.

Whos giving you all this information?

most of it seems pretty good

Frenchi are you still on about this stuff?

You know hard flaccid is a pelvic floor disorder issue not a hormonal imbalance — right?