Sexual Reboot Forum inositol

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    Brain Res. 1993 Dec 24;631(2):349-51.

    Myo-inositol reduces serotonin (5-HT2) receptor induced homologous and heterologous desensitization.

    Rahman S, Neuman RS.

    Faculty of Medicine, Memorial University, St. John’s, Nfld, Canada.

    The effect of myo-inositol was examined on 5-HT2 receptor mediated facilitation of NMDA depolarization of rat neocortical neurons in vitro. Myo-inositol (1-10 mM) potentiated the 5-HT facilitation, the potentiation increasing linearly with log 5-HT concentration. Myo-inositol also eliminated 5-HT induced heterologous desensitization of muscarinic and alpha 1-adrenergic receptor mediated facilitation. Our findings suggest that 5-HT induced homologous and heterologous desensitization results in part from depleting phosphoinositide substrate.

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    Inositol supplement could have an dramatic effect on serotonin level ?

    Did you test your inositol level with blood test ?

    I find the link inositol-spem-liver interesting and some guys think low level of inositol can cause depression and stress.



    Inositol is a strong link between sexual exhaustion, panic/anxiety/depression/social phobia, intestine, liver and mental tiredness.

    And it’s a major ingredient of sperm.

    Can sexual exhaustion can be considered as a depletion of inositol by excessive ejaculations and lowest metabolism of inositol of guys here ?




    Inositol is listed in two books that I’ve read about amino acid therapy. Both list it as as helping with stress, specifically by raising your GABA levels in the brain. According to The Edge Effect, GABA deficiency is the direct cause of anxiety and panic attacks.

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