Mix of propionyl-L-carnitne and L-arginine improves erection

Sexual Reboot Forum Mix of propionyl-L-carnitne and L-arginine improves erection

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    Give men with erection problems 250 mg daily of propionyl-L-carnitine [structural formula shown below] together with 2500 mg L-arginine and their sex life will improve. Researchers at the Sapienza University of Rome discovered this when they did experiments with 54 men aged between 35 and 75.

    In the Italian study, which will be published soon in Andrologia, the men were given a powder containing the two amino acids plus 20 mg of the vitamin B3 analogue niacin. That’s a low amount; multi-vitamin tablets usually contain more. The men dissolved the powder in a glass of water and drank this. The powder was supplied by Sigma-Tau, a manufacturer of carnitine analogues. The manufacturer’s name crops up surprisingly often in studies on the positive health effects of carnitine.

    L-Arginine is a precursor of NO. NO enhances the activity of the enzyme guanylate cyclase in the blood vessels, which in turn raises the concentration of cyclic guanosine monophosphate [cGMP]. CGMP helps blood vessel walls to relax. Erection medicines like Viagra and Cialis work via cGMP.

    Carnitine analogues, whether or not combined with niacin, boost fatty acid combustion in cells, and therefore also in the cells of the blood vessel walls. As a result of this fewer free radicals are produced and the blood vessels become more flexible. This is how carnitine strengthens the effect of L-arginine. In theory at least.

    And hey presto, it worked in the study too. After taking the supplement for three months, the average erection score [IIEF] had risen from 15 to 20. That means that the average man in the study started with an ‘average to considerable’ erectile dysfunction, and that improved as a result of supplementation to a ‘mild’ erectile dysfunction. An IIEF of 22-25 counts as healthy.

    Most of the test subjects indicated that they would like to continue using the supplement. Few side effects were observed.

    “In addition to first-line treatment in selected patients, the formulation tested may have a role as adjuvant therapy”, the researchers conclude.

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    Pistachio nuts versus impotence

    A small study done by doctors at Ataturk Teaching and Research Hospital in Ankara indicates that a diet containing pistachio nuts can help mild forms of impotence. A daily 100g of these nuts should be enough, according to an article in the International Journal of Impotence Research.

    The researchers did an experiment with 17 married men aged between 38 and 59, who had complained of impotence for at least a year.

    From the literature the researchers knew that there is a relationship between cardiovascular problems such as a high level of LDL [‘bad cholesterol’] and impotence. They also knew that a high intake of nuts has many positive effects on the cardiovascular system.

    So the researchers put two and two together and got the impotent men to eat 100 grams pistachio nuts with their lunch, every day for three weeks. Before the experiment started and at the end they completed a standard questionnaire with their subjects on impotence, the IIEF-15.

    The men’s scores improved considerably, as the table below shows. Their erectile function [EF] score rose from 12.1 to 21.4, going from ‘moderate dysfunction’ to ‘mild dysfunction’.

    In the figure above TC stands for total cholesterol and TG for triglyceride. The figure shows that the men’s cardiovascular scores improved.

    The researchers think that the relatively high L-arginine content of pistachio nuts has something to do with the improvements. This amino acid helps the blood vessels in the penis to dilate. The researchers also suspect that pistachio nuts contain substances that inhibit blood clotting and therefore make the blood thinner. This would also help erectile function.

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    I have low Arginine and other 11 aminoacids. I would encourage anyone suffering from a severe ED to have all the tests possible including the ones that are related with Nitric Oxide, like Arginine. Now I know that NO plays a important role in my dysfunction and I will fix it. I love pistachios, im gonna add the 100 mg to my daily foods.

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